The promise of high-content screening is the acceleration of discovery by extracting as much relevant information as possible from cells. Nevertheless, a large percentage of high-content screens analyse only a small number of image-based properties. As a result, valuable information from precious cells and disease models is not utilized. Operetta CLS high-content analysis system provides you the solution to monitor and evaluate your samples deeply. The instrument supports research from everyday assays to more demanding applications. It delivers a balance of flexible excitation, optics, and advanced software features to enable you to gain deeper biological insight from all your critical applications.
Fixed-cell assays
Up to eight high-power excitation sources and user-accessible emission filters enable maximum flexibility of fluorescent stains and labels, plus the system features widefield and spinning-disk fluorescent imaging.
Live-cell assays
The spinning disk confocal optics and synchronized LED illumination provide stable excitation and minimize phototoxicity and bleaching for meaningful live-cell assays. You can also choose brightfield or digital-phase contrast imaging modes.
Complex cellular models
The large-format sCMOS camera with water-immersion objectives provides sensitivity and high resolution, while advanced software helps you address the imaging and analysis challenges presented by complex cellular models.
Advanced assays
FRET is a powerful tool for investigating conformational changes and protein-protein interactions. The Operetta CLS system’s sensitive imaging and dedicated analysis tools for ratiometric imaging, facilitate robust results.
Phenotypic fingerprinting
The Operetta CLS combines high resolution imaging with advanced software tools to help create robust phenotypic fingerprints of the subtle differences at the core of successful phenotypic assays.
Time Movie Operetta NPs
Operetta (high content imaging) at Bright Night
Booking calendar
Extraordinary maintenance until April 27th
Loading...
6 September 2025
Sat
7 September 2025
Sun
8 September 2025
Mon
9 September 2025
Tue
10 September 2025
Wed
11 September 2025
Thu
12 September 2025
Fri
13 September 2025
Sat
14 September 2025
Sun
15 September 2025
Mon
16 September 2025
Tue
17 September 2025
Wed
18 September 2025
Thu
19 September 2025
Fri
20 September 2025
Sat
21 September 2025
Sun
22 September 2025
Mon
23 September 2025
Tue
24 September 2025
Wed
25 September 2025
Thu
26 September 2025
Fri
27 September 2025
Sat
28 September 2025
Sun
29 September 2025
Mon
30 September 2025
Tue
1 October 2025
Wed
2 October 2025
Thu
3 October 2025
Fri
4 October 2025
Sat
5 October 2025
Sun
6 October 2025
Mon
Fixed-cell assays
Up to eight high-power excitation sources and user-accessible emission filters enable maximum flexibility of fluorescent stains and labels, plus the system features widefield and spinning-disk fluorescent imaging.Live-cell assays
The spinning disk confocal optics and synchronized LED illumination provide stable excitation and minimize phototoxicity and bleaching for meaningful live-cell assays. You can also choose brightfield or digital-phase contrast imaging modes.Complex cellular models
The large-format sCMOS camera with water-immersion objectives provides sensitivity and high resolution, while advanced software helps you address the imaging and analysis challenges presented by complex cellular models.Advanced assays
FRET is a powerful tool for investigating conformational changes and protein-protein interactions. The Operetta CLS system’s sensitive imaging and dedicated analysis tools for ratiometric imaging, facilitate robust results.Phenotypic fingerprinting
The Operetta CLS combines high resolution imaging with advanced software tools to help create robust phenotypic fingerprints of the subtle differences at the core of successful phenotypic assays.Time Movie Operetta NPs | Operetta (high content imaging) at Bright Night |
Booking calendar
Extraordinary maintenance until April 27th
Loading...
6 September 2025
Sat
7 September 2025
Sun
8 September 2025
Mon
9 September 2025
Tue
10 September 2025
Wed
11 September 2025
Thu
12 September 2025
Fri
13 September 2025
Sat
14 September 2025
Sun
15 September 2025
Mon
16 September 2025
Tue
17 September 2025
Wed
18 September 2025
Thu
19 September 2025
Fri
20 September 2025
Sat
21 September 2025
Sun
22 September 2025
Mon
23 September 2025
Tue
24 September 2025
Wed
25 September 2025
Thu
26 September 2025
Fri
27 September 2025
Sat
28 September 2025
Sun
29 September 2025
Mon
30 September 2025
Tue
1 October 2025
Wed
2 October 2025
Thu
3 October 2025
Fri
4 October 2025
Sat
5 October 2025
Sun
6 October 2025
Mon