The promise of high-content screening is the acceleration of discovery by extracting as much relevant information as possible from cells. Nevertheless, a large percentage of high-content screens analyse only a small number of image-based properties. As a result, valuable information from precious cells and disease models is not utilized. Operetta CLS high-content analysis system provides you the solution to monitor and evaluate your samples deeply. The instrument supports research from everyday assays to more demanding applications. It delivers a balance of flexible excitation, optics, and advanced software features to enable you to gain deeper biological insight from all your critical applications.
Fixed-cell assays
Up to eight high-power excitation sources and user-accessible emission filters enable maximum flexibility of fluorescent stains and labels, plus the system features widefield and spinning-disk fluorescent imaging.
Live-cell assays
The spinning disk confocal optics and synchronized LED illumination provide stable excitation and minimize phototoxicity and bleaching for meaningful live-cell assays. You can also choose brightfield or digital-phase contrast imaging modes.
Complex cellular models
The large-format sCMOS camera with water-immersion objectives provides sensitivity and high resolution, while advanced software helps you address the imaging and analysis challenges presented by complex cellular models.
Advanced assays
FRET is a powerful tool for investigating conformational changes and protein-protein interactions. The Operetta CLS system’s sensitive imaging and dedicated analysis tools for ratiometric imaging, facilitate robust results.
Phenotypic fingerprinting
The Operetta CLS combines high resolution imaging with advanced software tools to help create robust phenotypic fingerprints of the subtle differences at the core of successful phenotypic assays.
Time Movie Operetta NPs
Operetta (high content imaging) at Bright Night
Booking calendar
Extraordinary maintenance until April 27th
Loading...
28 May 2025
Wed
29 May 2025
Thu
30 May 2025
Fri
31 May 2025
Sat
1 June 2025
Sun
2 June 2025
Mon
3 June 2025
Tue
4 June 2025
Wed
5 June 2025
Thu
6 June 2025
Fri
7 June 2025
Sat
8 June 2025
Sun
9 June 2025
Mon
10 June 2025
Tue
11 June 2025
Wed
12 June 2025
Thu
13 June 2025
Fri
14 June 2025
Sat
15 June 2025
Sun
16 June 2025
Mon
17 June 2025
Tue
18 June 2025
Wed
19 June 2025
Thu
20 June 2025
Fri
21 June 2025
Sat
22 June 2025
Sun
23 June 2025
Mon
24 June 2025
Tue
25 June 2025
Wed
26 June 2025
Thu
27 June 2025
Fri
Fixed-cell assays
Up to eight high-power excitation sources and user-accessible emission filters enable maximum flexibility of fluorescent stains and labels, plus the system features widefield and spinning-disk fluorescent imaging.Live-cell assays
The spinning disk confocal optics and synchronized LED illumination provide stable excitation and minimize phototoxicity and bleaching for meaningful live-cell assays. You can also choose brightfield or digital-phase contrast imaging modes.Complex cellular models
The large-format sCMOS camera with water-immersion objectives provides sensitivity and high resolution, while advanced software helps you address the imaging and analysis challenges presented by complex cellular models.Advanced assays
FRET is a powerful tool for investigating conformational changes and protein-protein interactions. The Operetta CLS system’s sensitive imaging and dedicated analysis tools for ratiometric imaging, facilitate robust results.Phenotypic fingerprinting
The Operetta CLS combines high resolution imaging with advanced software tools to help create robust phenotypic fingerprints of the subtle differences at the core of successful phenotypic assays.Time Movie Operetta NPs | Operetta (high content imaging) at Bright Night |
Booking calendar
Extraordinary maintenance until April 27th
Loading...
28 May 2025
Wed
29 May 2025
Thu
30 May 2025
Fri
31 May 2025
Sat
1 June 2025
Sun
2 June 2025
Mon
3 June 2025
Tue
4 June 2025
Wed
5 June 2025
Thu
6 June 2025
Fri
7 June 2025
Sat
8 June 2025
Sun
9 June 2025
Mon
10 June 2025
Tue
11 June 2025
Wed
12 June 2025
Thu
13 June 2025
Fri
14 June 2025
Sat
15 June 2025
Sun
16 June 2025
Mon
17 June 2025
Tue
18 June 2025
Wed
19 June 2025
Thu
20 June 2025
Fri
21 June 2025
Sat
22 June 2025
Sun
23 June 2025
Mon
24 June 2025
Tue
25 June 2025
Wed
26 June 2025
Thu
27 June 2025
Fri